Knowledge and Acceptance of HPV Vaccination among Early Adolescents in Secondary Schools
DOI:
https://doi.org/10.53770/amhj.v5i4.732Keywords:
Human Papillomavirus (HPV), HPV Vaccine, Knowledge, Vaccine AcceptanceAbstract
Human Papillomavirus (HPV) infection remains the leading cause of cervical cancer and continues to pose a public health problem in Indonesia. While previous studies have widely examined HPV-related knowledge and vaccines acceptance, evidence focusing on early adolescents within school-based vaccination settings remain limited. This study aims to analyze the relationship between the level of knowledge and acceptance of the HPV vaccine among third-grade junior high school students, a key target group for national immunization programs. A cross-sectional quantitative design was conducted among 48 students selected through total sampling. Data were collected using a structured questionnaire that measured respondent characteristics, knowledge levels about HPV, and acceptance of the HPV vaccine. Data analysis was performed univariately and bivariately using Fisher's Exact test with a significance level of 0.05. Most respondents were aged 14 years (60.4%), had high knowledge about HPV (72.9%), and showed positive acceptance of the HPV vaccine (64.6%). Bivariate analysis showed that students with high knowledge were 1.14 times more likely to accept the HPV vaccine positively than students with poor to moderate knowledge. However, this relationship was not statistically significant (p = 0.731; PR = 1.14; 95% CI: 0.67–1.94). There was no significant relationship between students' level of knowledge about HPV and their acceptance of the HPV vaccine. The study highlights the need for multidimensional intervention strategies involving parental engagement, school support, and health worker communication.
References
Amruddin, A., Muskananfola, I. L., Febriyanti, E., Atik Badi’ah, A., Pandie, F.R.,…& Djaniar, U. (2020). Metodologi Penelitian Kuantitatif dan Kualitatif. Bandung: CV. Media Sains Indonesia
Arna, Y. D., Janiarli, M., Kusumahati, E., Azis, M.N.S.A., Bobaya, J., … & Candriasih, P. (2024). Problematika Kesehatan Remaja. Cilacap: Media Pustaka Indo.
Ashrtika, V., Agustina, A., & Baharuddin, D. (2025). Determinan yang Mempengaruhi Keputusan Ibu terhadap Penerimaan Imunisasi HPV untuk Siswi Sekolah Dasar. INSOLOGI: Jurnal Sains Dan Teknologi, 4(3), 322-331. https://doi.org/10.55123/insologi.v4i3.5244
Baranga, S., Chioran, D., Balean, O., Dumitrescu, R., Popescu, R., Jumanca, D., ... & Galuscan, A. (2025). HPV Knowledge, Vaccination Uptake, and Salivary Diagnostics Among Dental Students in Romania. Vaccines, 13(6), 658. https://doi.org/10.3390/vaccines13060658
Burki, T. (2019). Vaccine misinformation and social media. The Lancet Digital Health, 1(6), e258–e259. https://doi.org/10.1016/S2589-7500(19)30136-0
Dionne, M., Sauvageau, C., Etienne, D., Witteman, H. O., & Dubé, È. (2024). Feasibility of interventions to increase HPV vaccination acceptability and coverage in school-based programs: Findings from a pilot study in Quebec, Canada. Preventive Medicine Reports, 48, 102931. https://doi.org/10.1016/j.pmedr.2024.102931
Ditjen P2P Kementerian Kesehatan Republik Indonesia. (2022). Petunjuk Teknis Pelaksanaan Bulan Imunisasi Anak Sekolah (BIAS). Jakarta: Ditjen P2P Kementerian Kesehatan Republik Indonesia. Retrieved from: https://kms.kemkes.go.id/contents/1716799954991-JuknisBIAS2022.pdf
Dubé, E., Gagnon, D., Pelletier, C., Comeau, J. L., Steenbeek, A., MacDonald, N., ... & Bettinger, J. A. (2024). Enhancing HPV vaccine uptake in girls and boys–A qualitative analysis of Canadian school-based vaccination programs. Vaccine, 42(26), 126425. https://doi.org/10.1016/j.vaccine.2024.126425
Halim, C. L., Kartarino, D., & Fadillah, Q. (2025). Gambaran Pengetahuan dan Sikap Siswi SMA Sutomo 2 Medan Terhadap Vaksinasi HPV. Journal of Syntax Literate, 10(10), 8433.
Hamidah, S., & Rizal, M. S. (2022). Edukasi Kesehatan Reproduksi dan Perkembangan Remaja di Panti Asuhan Yatim Muhammadiyah Kecamatan Gresik Kabupaten Gresik Jawa Timur. Journal of Community Engagement in Health, 5(2), 237–248. https://doi.org/10.30994/jceh.v5i2.384
Imelda, F., Karota, E., & Tarigan, M. (2024). Efektifitas Enpowerment Education terhadap pengetahuan Melakukan Vaksinasi HPV pada Remaja Putri. MAHESA : Malahayati Health Student Journal, 4(10), 4556–4568. https://doi.org/10.33024/mahesa.v4i10.15780
INSERM Collective Expertise Centre. (2021). Health education for young people: Approaches and methods [Internet]. Paris (FR): Institut national de la santé et de la recherche médicale. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK7118/
Jaiswal, R., Figueiredo, D., & Muraleedharan, M. (2025). Parental and young adults’ perspectives on STI vaccines and hesitancy: a pilot study. Discover Social Science and Health, 5(1), 169. https://doi.org/10.1007/s44155-025-00328-9
Kementerian Kesehatan Republik Indonesia. (2022). Penguatan Upaya Preventif Melalui Kemudahan Akses Vaksin HPV. Jakarta: Kementerian Kesehatan Republik Indonesia. Retrieved from: https://kemkes.go.id/eng/%20penguatan-upaya-preventif-melalui-kemudahan-akses-vaksin-hpv
Nguyen, H. T., Nguyen, K. C., Pham, T. Q., Nguyen, H. T., Hoang, A., Vu, T. T., ... & Vogt, F. (2024). Understanding Parental Decision-Making and Determinants of COVID-19 Vaccination for Children in Vietnam: A Cross-Sectional Online Survey. Vaccines, 12(11), 1266. https://doi.org/10.3390/vaccines12111266
Nkemngong, E. M., Tita, J. C., Nengieh, W. L., & Mesumbe, N. N. (2024). Social Media & Influence on Vaccine Hesitancy among Students of Higher Education Institutions in Cameroon: The Case of COVID-19 Vaccines. Advances in Journalism and Communication, 12(03), 451–473. https://doi.org/10.4236/ajc.2024.123025
Rahmah, B. P., Faris Naufal, M., Almerridho, V., Modjo, R., Kesehatan, D., Kerja, K., & Masyarakat, K. (2024). Faktor-Faktor Yang Memengaruhi Penerimaan Vaksin Human Papillomavirus (HPV) Di Negara-Negara Asean: Literature Review. Journal of Syntax Literate, 9(4), 2892. https://doi.org/10.36418/syntax-literate.v9i4
Susanti, F. (2022). Gambaran tingkat pengetahuan, sikap, dan perilaku orang tua terhadap pemberian vaksin covid-19 pada anak 6-11 tahun di Kota Palangka Raya. Skripsi. Poltekkes Kemenkes Palangka Raya.
Turiho, A. K., Okello, E. S., Muhwezi, W. W., & Katahoire, A. R. (2017). Perceptions of human papillomavirus vaccination of adolescent schoolgirls in western Uganda and their implications for acceptability of HPV vaccination: a qualitative study. BMC research notes, 10(1), 431. https://doi.org/10.1186/s13104-017-2749-8
Universitas Muhammadiyah Yogyakarta. (2025). Penerimaan Vaksin HPV di Indonesia Masih Rendah, Faktor Sosiokultural Jadi Pengaruh Utama [Internet]. Yogyakarta: UMY. Retrieved from: https://www.umy.ac.id/penerimaan-vaksin-hpv-di-indonesia-masih-rendah-faktor-sosiokultural-jadi-pengaruh-utama/
Wantini, N. A., & Indrayani, N. (2020). Kesediaan Vaksinasi HPV pada Remaja Putri Ditinjau dari Faktor Orang Tua. Jurnal Ners Dan Kebidanan (Journal of Ners and Midwifery), 7(2), 213–222. https://doi.org/10.26699/jnk.v7i2.art.p213-222
Wantini, N. A., & Indrayani, N. (2020). Rendahnya Kesediaan Vaksinasi HPV pada Remaja Putri. Jurnal Kebidanan Indonesia, 11(1), 69-78. Retrieved from: https://ipv6.jurnal.stikesmus.ac.id/index.php/JKebIn/article/view/327
WHO. (2022). Immunizing against HPV. Geneva: WHO. Retrieved from: https://www.who.int/activities/immunizing-against-hpv
WHO. (2024). Human Papillomavirus and Cancer. Geneva: WHO. Retrieved from: https://www.who.int/news-room/fact-sheets/detail/human-papilloma-virus-and-cancer
Yunus, M., Alfarisi, R., Hermawan, D., & Megarahayu, S. (2024). Hubungan usia dan pengetahuan dengan persepsi petugas kesehatan terhadap vaksinasi Covid-19. Journal of Community Health Issues, 1(2), 66-75. https://doi.org/10.56922/chi.v1i2.1122
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