Differences in Bleed Sedimentation Rate and Hematocrit Values in Chronic Kidney Failure Patients Examined Before and After Hemodialysis at Tabanan Regional Hospital

I Made Dwipa Cahyana; Heri Setiyo Bekti; I Gede Sudarmanto

doi:10.53770/medica.v6i2.501

Authors

I Made Dwipa Cahyana Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia
Heri Setiyo Bekti Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia
I Gede Sudarmanto Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.53770/medica.v6i2.501

Keywords:

Chronic Kidney Disease, Hemodialysis, Hematocrit, ESR Changes

Abstract

Chronic Kidney Disease (CKD) is a pathological condition that is irreversible and has various underlying causes. The diagnosis is based on structural or functional abnormalities of the kidneys, with the primary criterion being a glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m² for more than three months. Common symptoms include fatigue, loss of appetite, and muscle cramps. Management of CKD consists of two stages: conservative treatment aimed at slowing disease progression and renal replacement therapy, such as dialysis or kidney transplantation. Erythrocyte Sedimentation Rate (ESR) and Hematocrit (Hct) tests are important for detecting decreased erythropoietin production, which impacts red blood cell formation. The objective of this study was to examine the differences in ESR and Hct values in patients with chronic kidney disease before and after undergoing hemodialysis. The study employed a pre-experimental design using a One-Group Pretest-Posttest approach, involving a single experimental group without a control group. Measurements were taken both before and after the intervention. The results from 10 CKD patients at Tabanan Regional Public Hospital indicated that all respondents (100%) had elevated ESR levels both before and after hemodialysis. In contrast, Hct values decreased following hemodialysis, which is likely due to reduced erythropoietin production associated with CKD, leading to anemia. In conclusion, no significant difference was observed in ESR values before and after hemodialysis. However, there was a notable difference in Hct values, which declined after the procedure.

References

Amalia, A., & Apriliani, N. M. (2021). Analisis Efektivitas Single Use dan Reuse Dialyzer pada Pasien Gagal Ginjal Kronik di RSUD Mardi Waluyo Kota Blitar: Analysis of the Effectiveness of Single Use and Reuse Dialyzers in Patients with Chronic Kidney Failure at Mardi Waluyo Hospital, Blitar City. Jurnal Sains dan Kesehatan, 3(5), 679-686.

Angraini, R., Harun, S., & Asnindari, L. N. (2021). Faktor–faktor yang mempengaruhi kualitas hidup pasien penyakit ginjal kronik yang menjalani hemodialisa literature review. Skripsi thesis, Universitas 'Aisyiyah Yogyakarta.

Arvianti, V., Septiani, S., & Yansen, A. (2021). Perbedaan Kadar Hemoglobin pada Penderita Gagal Ginjal Kronik Sebelum dan Setelah Melakukan Hemodialisa. Jurnal Insan Cendekia, 8(2), 146-151.

Chairani, C., Susanto, V., Monitari, S., & Marisa, M. (2022). Nilai Hematokrit pada Pasien Hemodialisa dengan Metode Mikrohematokrit dan Automatik. Jurnal Kesehatan Perintis, 9(2), 89-93. https://doi.org/10.33653/jkp.v9i2.872

Ernawati, E. (2019). Gambaran Hasil Pemeriksaan Hematokrit secara Manual dan Automatik pada Pasien Rawat Inap di RSUD Lubuk Sikaping. Sekolah Tinggi Ilmu Kesehatan Perintis Padang Padang 2019. Skripsi thesis, Stikes Perintis Padang.

Haryanti, I. A. P., & Nisa, K. (2015). Terapi konservatif dan terapi pengganti ginjal sebagai penatalaksanaan pada gagal ginjal kronik. Majority, 4(7), 49-54.

Hidayah, N. (2018). Perbedaan Nilai Hematokrit Darah Kapiler Menggunakan Hematologi Analizer Dengan Manual Mikrohematokrit. Skripsi, Universitas Muhammadiyah Semarang.

NKDEP. (2015). Chronic kidney disease and diet: assessment, management and treatment. National Kidney Disease Education Program.

Nuroini, F., & Wijayanto, W. (2022). Description of Urea and Creatinine Levels In Chronic Renal Failure Patients at Wiradadi Husada Hospital. Jambura Journal Of Health Sciences and Research, 4(2), 538-545.

Nuratmini, P. N. (2019). Gambaran Kadar Ureum dan Kreatinin Serum pada Pasien GGK setelah terapi Hemodialisis di RSD Mangusada, Kabupaten Badung. Diploma thesis, Poltekkes Kemenkes Denpasar.

Rahmawati, N. A., Listiana, L., & Mu’minin, U. (2012). Analisa Nilai Laju Endap Darah Pada Pasien Gagal Ginjal Kronis Yang Rawat Inap DI RSUD Dr. Soetomo Surabaya. Skripsi, Universitas Muhammadiyah Surabaya.

Rosini, D.D., Aini, A., & Ramadanti, E. (2020). Efektivitas Hemodialisa Berdasarkan Parameter Hemoglobin. Jurnal Analis Medika Biosains (JAMBS), 7(2), 146-152

Rustendi, T., Murtiningsih, M., & Inayah, I. (2022). Kualitas Hidup Pasien Gagal Ginjal Kronis yang Menjalani Hemodialisa. Mando Care Jurnal, 1(3), 98-104.

Schonder. (2016). Chronic Kidney Disease: Progression-Modifying Therapies In Pharmacotherapy A Pathophysiologic Approach. 8th Edition. The McGraw Hill Companies, Inc.

Wong, O. A., & Sarjana, D. S. S. M. G. (2017). Analisis Perubahan Hemoglobin Pada Pasien Gangguan Ginjal Kronik (GGK) Yang Menjalani Hemodialisis Selama 3 bulan di Rumah Sakit Perguruan Tinggi Negeri (RSPTN) Universitas Hasanuddin (UNHAS) makassar. Skripsi, FK Universitas Hasanuddin Makasar, 1-83.

Yuniarti, W. (2021). Anemia in Chronic Kidney Disease Patients. Journal Health & Science: Gorontalo Journal Health and Science Community, 5(2), 341-347.

Zainabiah, S. (2019). Gambaran Hasil Pemeriksaan Laju Endap Darah (LED) Pada Penderita Penyakit Gagal Ginjal Kronik Di Salah Satu Rumah Sakit Tasikmalaya. Diploma thesis, STIKes BTH Tasikmalaya.