Factors Associated with Hyperbilirubinemia in Newborns at Tanjungpura University Hospital, Pontianak

Authors

  • Anggita Ria Panjaitan Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Pontianak, Pontianak, West Kalimantan, Indonesia
  • Sri Tumpuk Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Pontianak, Pontianak, West Kalimantan, Indonesia
  • Emilda Sari Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Pontianak, Pontianak, West Kalimantan, Indonesia
  • Mohd Yunus Faculty of Medicine, Jalalabad State University, Kyrgyzstan

DOI:

https://doi.org/10.53770/medica.v7i1.485

Keywords:

Hiperbilirubinemia, Newborn, Neonatal Death

Abstract

In Indonesia, neonatal death is often caused by low birth weight, asphyxia, birth trauma, hyperbilirubinemia, infections, and congenital abnormalities. Hyperbilirubinemia in neonates generally occurs due to the immaturity of organs in processing bilirubin, with phototherapy as the primary treatment. Recent studies have shown an increase in cases of hyperbilirubinemia at Tanjungpura University Hospital in Pontianak, highlighting the need for further research on the factors influencing this condition. The aim of this study is to analyze the factors associated with hyperbilirubinemia in newborns at Tanjungpura University Hospital in Pontianak. This research used an analytical observational design with a cross-sectional approach. The sample consisted of 67 respondents selected through total sampling. The distribution of maternal gestational age showed 49.3% preterm and 50.7% term. Of the respondents, 50.7% had ABO incompatibility, while 49.3% did not. A total of 58.2% of the newborns had normal birth weight, while 41.8% did not. Regarding delivery type, 67.5% were delivered by cesarean section (C-section), and 34.3% by normal delivery. The results of the Chi-Square Continuity Correction test showed p=0.038 for gestational age, p=0.018 for ABO incompatibility, p=0.001 for birth weight, and p=0.202 for delivery type. In conclusion, there is a significant relationship between gestational age, ABO incompatibility, and birth weight with the occurrence of hyperbilirubinemia, but no significant relationship with the type of delivery.

References

Akbar, T. I. S., Ritchie, N. K., & Sari, N. (2019). Inkompatibilitas ABO Pada Neonatus Di Utd Pmi Kota Banda Aceh Tahun 2018. AVERROUS: Jurnal Kedokteran Dan Kesehatan Malikussaleh, 5(2), 59-75. https://doi.org/10.29103/averrous.v5i2.2081

Aldina, M., Utami, K., & Reski, S. (2022). Hubungan status gizi ibu dan jarak kelahiran dengan kasus berat badan lahir rendah di rsud abdoel wahab sjahranie samarinda. Formosa Journal of Science and Technology, 1(5), 411-420. https://doi.org/10.55927/fjst.v1i5.1199

Al-Hanawi, M. K., Khan, S. A., & Al-Borie, H. M. (2019). Healthcare human resource development in Saudi Arabia: emerging challenges and opportunities—a critical review. Public health reviews, 40, 1-16. https://doi.org/10.1186/s40985-019-0112-4

Asnidar & Asdinar. (2017). Relationship Between Parents And Events Low Birth Weight. Jurnal Life Birth, 1 (1), 20-27.

Bhutani, V. K., Zipursky, A., Blencowe, H., Khanna, R., Sgro, M., Ebbesen, F., Bell, J., Mori, R., Slusher, T. M., Fahmy, N., Paul, V. K., Du, L., Okolo, A. A., de Almeida, M. F., Olusanya, B. O., Kumar, P., Cousens, S., & Lawn, J. E. (2013). Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels. Pediatric research, 74 Suppl 1(Suppl 1), 86–100. https://doi.org/10.1038/pr.2013.208

Fanni, D. R. Y. & Adriani, M. (2017). Hubungan Usia Gestasi Dan Kadar Hemoglobin Trimester 3 Kehamilan Dengan Berat Lahir Bayi. Amerta Nutrition, 1(3), 162. https://doi.org/10.20473/amnt.v1i3.6241

Gerungan, G., Wilar, R., & Mantik, M. (2022). Mekanisme Terjadinya Hiperbilirubinemia Pada Bayi Berat Lahir Rendah. E-Clinic, 11(1), 80-86. https://doi.org/10.35790/ecl.v11i1.37828

Indriyani, R. And Alvianti, H. (2021). Umur dan paritas ibu sebagai faktor yang berhubungan dengan bayi berat badan lahir rendah. Jurnal Kebidanan, 11(2), 73-81. https://doi.org/10.35874/jib.v11i2.899

Kementerian Kesehatan Republik Indonesia. (2022). Laporan Akuntabilitas Kinerja Instaansi Pemerintah (LAKIP) Direktorat Gizi dan Kesehatan Ibu dan Anak Tahun Anggaran 2022. Jakarta: Kementerian Kesehatan Republik Indonesia.

Khotimah, H. & Subagio, S. U. (2021). Analisis Hubungan Antara Usia Kehamilan, Berat Lahir Bayi, Jenis Persalinan Dan Pemberian Asi Dengan Kejadian Hiperbilirubinemia. Faletehan Health Journal, 8(02), 115-121. https://doi.org/10.33746/fhj.v8i02.146

Kozier. (2011). Buku Ajar Fundamental Keperawatan Konsep, Proses dan Praktik. Jakarta: Buku Kedokteran EGC.

Lamdayani, R., Angeriani, R., & Nopia, E. (2022). Faktor-Faktor Yang Berhubungan Dengan Hiperbilirubinemia Pada Bayi Baru Lahir. Cendekia Medika: Jurnal Stikes Al-Maarif Baturaja, 7(1), 50-64.

Pratiwi, G. N. & Kusumaningtiar, D. A. (2021). Kejadian Hiperbilirubin Bayi Baru Lahir Di Rs Swasta Jakarta. Jurnal Kesmas (Kesehatan Masyarakat) Khatulistiwa, 8(2), 72. https://doi.org/10.29406/jkmk.v8i2.2502

Putri, R., Hasanah, N., & Ahsan, A. (2017). Hubungan Jenis Persalinan Terhadap Keberhasilan Inisiasi Menyusu Dini (IMD) Di RSUD Bangil Kabupaten Pasuruan. Majalah Kesehatan, 4(4), 183-192. https://doi.org/10.21776/ub.majalahkesehatan.2017.004.04.22

Santosa, Q., Mukhson, M., & Muntafiah, A. (2020). Evaluasi Penggunaan Fototerapi Konvensional Dalam Tata Laksana Hiperbilirubinemia Neonatal: Efektif, Tetapi Tidak Efisien. Sari Pediatri, 21(6), 377. https://doi.org/10.14238/sp21.6.2020.377-85

WHO. (2024). Newborn Mortality [Internet]. World Health Organization. Retrieved from: https://www.who.int/news-room/fact-sheets/detail/newborn-mortality

Widadi, S. Y., Puspita, T., Alfiansyah, R., Rilla, E. V., Wahyudin, W., & Nurazizah, S. (2023). Hubungan Berat Badan Lahir Rendah Dengan Kejadian Hiperbilirubin Di Ruang Perinatologi Rsud Dr. Slamet Garut. Syntax Literate ; Jurnal Ilmiah Indonesia, 8(2), 1600-1612. https://doi.org/10.36418/syntax- literate.v8i2.11458

Widhiastuti, E. (2024). Light‐Emitting Diode Phototherapy For Neonatal Hyperbilirubinemia: A Literature Review. Holistik Jurnal Kesehatan, 17(9), 817-826. https://doi.org/10.33024/hjk.v17i9.13064

Yasadipura, C., Suryawan, I., & Sucipta, A. (2020). Hubungan Bayi Berat Lahir Rendah (BBLR) Dengan Kejadian Hiperbilirubinemia Pada Neonatus Di RSUD Wangaya, Bali, Indonesia. Intisari Sains Medis, 11(3), 1277-1281. https://doi.org/10.15562/ism.v11i3.706

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Published

2025-01-31

How to Cite

Panjaitan, A. R., Tumpuk, S., Sari, E., & Yunus, M. (2025). Factors Associated with Hyperbilirubinemia in Newborns at Tanjungpura University Hospital, Pontianak. MEDICA (International Medical Scientific Journal), 7(1), 24–31. https://doi.org/10.53770/medica.v7i1.485